The 440 has a 6.760" rod and the 400 has a 6.358 in rod.
The 400 ends up being about about 60 pounds lighter and has the biggest bore of any Mopar. (4.340) The rod journals are the same,but the mains are smaller (2.625) vs. (2.750). So you will need to have the mains turned down to the 400 dimension,then you have to bore it .030 to get 451 cubic inches....But don't use the .030 bore size: a 4.370 bore is very difficult to find rings for. Use .040 pistons and use the +.060 440 rings. (4.380). Use the 400 rod (the rod ratio is still 1.70) and there is an inexpensive piston now available from Keith Black, the KB 215,for $374.99 from Summit.
You will have a lower rotating weight, the lower deck height allows for a more compact piston which in turn reduces the piston weight significantly. The longer 440 rod and longer stroke of the 440 crank also means that a 451 has lighter pistons than a stock 400. The typical piston/pin/rod assembly in a 400 weighs 1930 grams. The same assembly for a 451 using stock 440 rods weighs 1630 grams. (This can be made even lighter by using 0.990 pins) The reduction of 300 grams per cylinder means a weight reduction of 2400 grams, or 5.3 pounds from the assembly. An additional amount must be taken off of the crank counterweights to balance the motor. This amount is 1060 grams or 2.33 pounds for the above configuration. That means that the 451 rotating assembly is 7.6 pounds lighter than a 400.