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Set the timing correct and a stock rad.. generally no issues. A good flowing 180/190 theromostat and have at'r. Not enough details in your post for a real conclusion...
I have this same combo, minus 14 cubic inches, no shroud, 56 year old radiator and clutch fan and am doing fine. Granted it’s New England and I usually don’t drive it too far over 90 degrees.
Roadrunner/magnum cam, 9.25:1, Holley 3310, CH4B. Open chamber heads. Initial timing about 16, all in at 38. Lots of vac advance, probably 60 total when it’s all in, Ported.