For my lightly modded 71 440 in my 70 V code Roadrunner, the biggest improvements in performance came when I got the center and outboard carbs idle mixture screws tuned correctly, the outboard linkage was a little sticky when I first got the car but a slight adjustment of the rods that are on the driver's side fixed that, went to #65 jets in the center carb (I'm at sea level) and I have a 509 lift 292° duration purple stripe cam with headers, 4 speed and a 3.54 Dana, and a FBO ignition system helped too vs the Chrysler electronic ignition.
Good luck!