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More gear. .......

You mentioned a Holley 750. Is it a double pumper or vacuum secondary? A vacuum secondary with a spring in it that is too stiff may never pull the secondaries open all the way. That will kill a bunch of power. What exhaust do you have? Back in the 80s, my 440 powered 71 RR had two inch exhaust with glass packs. First trip to the track went 14.90s at 93 mph. Second trip to the track I bumped up the timing a few degrees and opened up the headers. 14.14 at 102 mph, spinning the heck out of the tires.
 
750 holley double pumper
Open headers

What total degrees should I be running?
 
What ever it likes. That will have to be found. Anything else would be just a recommendation.
But there are proven maximums.
 
750 holley double pumper
Open headers

What total degrees should I be running?

Start at 34° total and work your way up. I've experimented a lot and my particular combo likes 36° with 91 Octane No Ethanol.
 
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