My road runner is running a 77 motorhome 440 in it. Although I didn't do the swap, the p.o. did, the main things I had to do were to replace the valve covers with car style ones. The motor home engines usually have the van style valve covers which don't have an oil fill cap but rather used the long tube which ran to the front of the engine compartment. Also, mine had a long metal tube which wrapped around the carb for the power brake booster. I just cut it off and pointed it at the brake booster and resolved that problem. Mine does have the different style water pump, but it works well with my radiator.
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This is the result although I have cleaned up a few things since.