This doesn't make much sense to me. I suspect you have a smogger 400 with the original cast pistons and lower end. I have nothing against cast pistons, and have tortured a set on a mild 383 and they never complained, but why do all that high RPM power stuff and keep the same bottom end? Is this for a street car? Then this even makes less sense. My approach would be to build an engine that optimizes power from off idle to 5500 and preserve drivability. Maybe the Hughes cam is magic and will keep the cylinder pressure and idle vacuum up, but typical big cam / low compression situations make for a pretty lazy low end combo. They also throw all the factory carb seting out the window along with the advance curve. I'd forget about max HP and focus on more average power in the low to mid range if this will be a street car. That's not to say a set of better heads won't help, but tread lightly on the cam.