Guys,
the definition of a seasoned block simply means a used block that has no significant defects from neglect/abuse or catastrophic failures over the course of it's life cycle. A good used block is preferred because thermally cycling the casting (driving the car) will result in settling, or shifting, of the core over time, and will provide a solid platform for future machining and builds - because the casting will have 'settled'.
In other words, as a machinist and builder, you can rest assured that there will be no (or minimal) additional core shift during the machining, build, and operation of your fresh engine.
Remember, a brand new casting that has not been thermally cycled, will tend to settle/shift once it's thermally cycled. If you start with a new (non-race) casting and complete your machining tasks to support a "brand new" build, there's a chance core shift, from thermal cycling, could haunt you later in the form of failed head gaskets; excessive leak down on some, or many, cylinders; erratic bearing wear patterns; etc. Ask me how I know...
I can also tell you this; the newer, high nickel, race blocks do not suffer from the same kind of core shift we're used to seeing in the older castings, especially the World Products castings from Bill Mitchell. Unfortunately, Chrysler found someone that will do these block for a few bucks cheaper than Mitchell, so we can all expect another round of casting failures, as Chryslers 'bean counters' give the new foundry and opportunity to "flush out" their casting issues - over time - and at our expense... Anybody remember how the original siamesed castings failed ? Well, Chrysler's at it again...
This "seasoned blocks" discussion applies mostly to our "older" stock of engine blocks and most non-race castings.
I hope this helps.
Southernman