From the Eagle website:
Now that we are on the subject of limitations, let's explore some of them so you'll know what you're up against. The engineers that designed each block never intended for stuff like this, but they did leave some room for improvements. Some engines more than others. Not all engines are created equal. The longer stroke crankshaft and the rods have to be able to rotate in the block without running into things like the crankcase walls, bottom of the cylinders, oil pump bosses or pickups, oil pans, windage trays, main cap girdles, or even the camshaft!
Ouch!
The camshaft!? Really?
It's relatively easy to get out the grinder and grind away parts of the crankcase, notch out the bottom of the cylinder walls, buy a different oil pan or pickup, or buy a different main cap girdle. But you can't exactly clearance the camshaft now can you? Fortunately the only engine that has this problem is a Chevy small block. Unfortunately that is the most common engine people build stroker engines out of! For the Chevy small block, that is the single biggest obstacle to overcome when building a stroker. Design changes in the connecting rod and/or camshaft (smaller base circle) can help with this, but they can only go so far. You will have to consult different component manufacturers to see just how far you can go.
Since I build all kinds of motors, I have seen this on a Chevy. I guess Mopar has enough room, so it is okay. I was just trying to help with an idea to check.
