A standard 426 Hemi rod makes the six pack rod look like a toy. It's probably a couple hundred grams heavier and the hemis revved just fine. The Grand National rod is even a hundred grams more, I just compared the difference the other day.
My six pack engine revs great with six pack rods. With Wiseco pistons, my bobweight total is less than a stock 440 piston/rod assembly. I had to remove quite a bit of material on the counterweights to balance the crank with the external balancer. I could have gone internal on the front, but I wanted the correct looking balancer.
The six pack rods tend to be heavy on the pin end. Using a nice, light piston pretty much cancels out the extra weight.