This question has been beaten nearly to death, both here and elsewhere out there honestly.
Heck, even Nick's garage has done entire episodes directly comparing the two on the same near-stock
engines back to back.
The simple consensus is - if the engine is anywhere near stock (or even mildly modified), on the street
the manifolds simply do not give up enough HP to make headers worth the aggravation and expense.
Yes, headers do contribute a little to the sound of the exhaust as well, but not enough for most to even
detect honestly...
That said, Fred has some of those big tube goofy Hedmans on him that I got with him 13+ years ago
that refuse to rot so I can make the case to replace them.
I despise the dang things honestly (along with the 3" dual exhaust all the way out the back); the whole
exhaust is overkill for what is only about a 425-450hp engine on a good day and makes any sort of work
around the car a colassal pain in the *** - not to mention, the exhaust bakes my wife and I like taters on
a typical summertime drive to boot.
If I raced Fred - if he had the cajones to warrant them - I'd be fine with headers.
I don't - HE doesn't - so I'm not.