The AFR Black Hawk 224 CNC Gen 3 heads are advertised to flow 390 cfm @ 0.700" lift
The 212 head looks good too, with a bit better low lift flow @ 0.400" and below. 0.500" is almost the same. Just thinking of swaps with stock cam.
The heads are a bit pricy $2,041 each, but come fully assembled with good parts.
Ported Big Block Mopar heads that flow 390 @ 0.700" are going to cost about the same. Thinking of what my Hughes CNC ported Victor MW heads cost, plus springs, retainers and such.
Just thinking that with heads that flow and cost about the same, likely not a big difference in peak power so looking at other considerations.
The early 5.7 heads are nothing special, the later Apache heads are really good. CNC ported flow around what the Trick Flow big block heads flow.
The larger CID of the big block would have more low end torque and wouldn't have to rev as high as the smaller Gen 3 engine.
Aftermarket roller rocker arms for the Gen 3 hemi can get expensive, 4 shafts vs 2 shafts for the big block wedge. Might be a consideration when building big power.
I think if you want old school big block power and torque, Normally Aspirated, simple wiring, and using stock k-frame / mounts then do the big block.
If you want more of the modern pro tour type car with all the computerized EFI & ignition, and want to later use forced induction, then the Gen 3 Hemi would be my choice. Maybe with an aftermarket K-frame