I was born in Erie, PA, but we moved to upstate NY (Albany area) before my 1st birthday. We have east coast roots - my parents grew up in Philadelphia, so that's where most of our relatives were. So, when we moved to Omaha in '73, when I was 10, it was a BIG change. Then we moved to Wisconsin in '78 when I was 15. I lived with my brother in northern CA (Silicon Valley) the spring and summer of '83 with plans to stay out there, but I came back to WI for a job opportunity later that year. CA had great weather, though! I went to South Dakota in '85 for college and stayed there until early 1990, when my wife and I relocated back (for me) to WI. Been here ever since.
Pros of our rural area: Low property taxes, no gangs, no traffic, clean air, very pleasant surroundings, very safe. We're within an hour of Milwaukee, Madison, and Green Bay, and 3 hours from Chicago, so we're nicely positioned in the state without having to live with the cons of those areas. Ethanol free gas is available all over the place around here, and no vehicle inspections. Less people around here is another real plus.
Cons: Winter sucks - WAY TOO F'NG LONG! Not only that but the salt on the roads is a major drag. The humidity in the summers has become more and more of an issue, too. It didn't used to be too bad. We're also a little too far away from my car buddies in the SE part of the state like Thunderlugs, eric383, and Sonny Black, to name a few. Having to put the old cars into winter hibernation is also a downer.
Overall, the pros outweigh the cons and no reason to leave a great job to relocate. My number one gripe is the winters as I get older, but the midwest is a nice place to live.